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Express Scripts/City of Carmel _11... 'A EXPRESS SCRIPTS~ .4I!El:I'" ~Pfl.OV..IE. D~ TO IFOltM IV: . \ ' Dec.mtJer~, 2608 City 01 C.rm,I,:lndi.na One Civic:Squar~ Carmel.IN'4.803.2 Alln; Cily 01 Carm,l, IndiaM We arflple~se~ lha.l, YQlJ'~a\le.agzea_d (o_,new terms:_urlder your Ma~aged.Prescriplion Dru~:Pi9g.r"f1:'IA.greeiTIen!wilh-E_:;(pressS{:'npi Thi5le~er wm servij 10 confirm ttlat Expfes::;,Scnplswill c{]ntinw~:to m":inage lhe costs arid utilllBli-an ol;youf preschplion,druQ.bemifll plan. While iM,coniracling process ~asbaen i~itialtra, a'de~inlllije,agrsemenllcDnlracl has r10Ibeen- e;(ecu~ed, In:Qrde-r la{ExpiesS:Scrip~ 10 be" 'able toimpremen'i agreed.'LlpO,ri,cliange3 10 yuur'pr-esc@troo d~g program withoul a sig~gd agreement; Expr.e?s ~Scrip~s,reqlli~~s.w len conrirmat1o!1 from,yo_ucQnceming't~_~fi~all~ial terms o!{lur ~rrangemenl. Subject 10 the~reqLiiraments~elow,_ E~pre55,Scripts l,'Iilfimph3manllheJ,inanciaJ ieiTl1:S sei.loithlri'lhe attached,to be effedfve'J-iinu'a" ~i. . 2009 ~r 10 b~5lness daY5',~o!(owi~g our, recelpCaf 'hisJet:er' signed,by an ilPP'_Opr?,te ~ifjcef of YOj.lrorga~.i~aliOil II recdv~c! af.taJ Jan 1:~2009, .In:addl!lQn, Ihjspricing Ls-conditioned LJpgQ a;t~re.eYf':ar e!t~n-si.Qn wilh'ESI'as,yolH,excl,!,JsivB'P.BM., DLJe,to,lhe well pu_btfcizea court settlem~nt_underway regarding the, use of'AWP:Pncin~8e~c~marks as a'basis lor-pharmaceutical nCing,1 lhe R0dng, indices ;"used ~lof"~is .Ag~~eem~nl may,cfiarge'du-e 10 facjors outsida,ttle':c_onlrol'-o( you ,and ESI.:, Hbenchmark,changes.afe' ma~.e under lh.;SA9re-emen1'and'an~ S\Jbseque~t,deffli!lj,~e:q~I'I~[aCI eX,ecule~ b~(~~e~ In~,pa~[~S,,9~( inlap!_,s,t9):,A!nt,8inF:.iel.ng, ~lJ;l?ility, as Inlended ",.d',nol la,advanlage,e1lh,r party 10 IQ' delnmenla! Iheother, Should a change.occ,UT, ESr,nall prov,de}ou Wllh'alldast 90 .days n6lice,ol"thechange(or if_ such ilaticeis.J1ot practicable" as.mucn-notice'as'isreasonable;under I~e circurnSla"nce:s), and lJe will providB wrillen,financlal iilustralions d~mons'raling. the: prfce, .neutral im~:actQi. th& drugfjleso~rce'or- im:le:r: change" (e,g:,.spe~cif ,::.'drug . examples.). . Expr~ssScr"ipis;'pOlicy prohibits the,wocessing of-subsidy rap;orts as:v/etl as p-aymei1ls-018u~hiterT)s'as'ieb,ates, guaranlees,comm ~?ions ..,.' or olhe"r simjlarpa~merlls'unm a co,r.tra~lisr~I_ly E:',(~~uted.. P1ea;i~ al~ono,!E J~al ~~, !Jl~Y nOI,~~'a~I~_,tobill lor ~ar~fac.l~rer.reb<;1tes [or any.. QUarter,for which. wnll~~ co~traClis 1]9.1 in pl~ce, ~o!.! aleg..1 '. Oillr.ici i.' nol in Plec. e by th.' lim.e we billlhe mAnUI'iclurers.1u'lBII.y wiihin Iwo weeks ofine end oi a,calen-dar quarler) we may'no1 be atllB to bill lor reba1es for your,program Icrlhal-quarter. . Expres~ Scnpls loolo;s ~orwar~ 10 a long and mutually salisfyi_ng,worJ.:II:lg:relat~onshipw1ln YO!1,(tyoy have ?.ry.gue~tr~D,?i pl~as~. ~qfilH.~l Jeffer,Grahama1:314-996-o917, Ple~se;.sign and return th.15Ie1t~r ~i!l (~~,19 EUen Wynne al 80O-2.a7-Q3~g:afld meillhe original la' er allenlion'atth~ ~ddr~:5.sbeI9~'.( , Company: Signatu~E'; : Printed Name: Title: Oflr: Expr~ss v.:':J.y;~".st.. Lotlt~~ MO '6,1 121 ,;3 14:1;l~.(;;0900:pwww.e:q:ires~~&ciiprs.com IN WITNESS WHEREOF, the parties hereto have made and executed this Agreement as follows: CITY OF CARMEL, INDIANA by and through its Board of Public Works and Safety BY: BY: Authorized Signature Printed Name: Title: FID/TIN: '14 p. '1 at!:> SSN if Sole Proprietor: Date: IZ:\[ !k<sIMr o.:...n.......1.Pr"I~i"'LOI So:nO''''\FORM5\Pror~",,>.J s~~~ fO.R.'>l Rc. 2OU'l-dox: 111'n1lO~ o;H f"rI-C) 8 -,.... ,. EXPRESS SCRIPTS@ .",,~ PHARMACY BENEFIT MANAGEMENT SERVICES ProCING SUPPLEMENT. FOR CITY OF CARMEL SEPT. 9TH, 200.8 Copyrighi'ro ~OO8'E~p.r~$!j^.Sc,~ipt~! l_nc",'A!1 rig~l$reser\.'Nt., ThisdocLlm~"-1 is'p.r~prietllrY'aIld {:annden_ti~l_and.c.Hlllot-be i;opied or repr(}duced ",,;ilboutprior v;.rjtren'['irrniSsion'~of.Ex:pr-l'ssSc:ripts.lril. This"dQClLlne-nt has been 'deiivrred'lolhc_ redpiellt ~Qldy 'r:Or.thepurpl.1se:Of permitting the recipient . '10;ev.lli.i~ie'1l' poti'n(i~[i:rdatiijnshtp '~i,!I!Exr>res5 Scripts;"lne: All otber t15eS prl:.hibifecl. RETAIL PHARMACY NETWORK AND HOME DELIVERY PRICING 8lmefilPlan ,- "',~ -..,-." --. 2'TierF'li;,Oesjaril 3-TierF'lan Oesian'with'less,than'$15.00 Differential ~H[lm'eiDeliverY Horrie,Delivery, 'Traditional; . Retail :[riscouriis"~"-' .- .". '~".' ., Mi~i~u~nJi~9'.tS ,-~:: ... . ..- cjtHs'counts- l::ess'than'35 '. ....r '--- . . . days'sii~pW . . Pricing The lower of AWl". AWp.24% AWp-17% 17% or U&C Brands Dispensing fee $1,501Rx $OIRx $1.50IRx Administrative fee $O/Rx $O/Rx $O/Rx The lower of AWl". The lower of AWl". The lower of AWl". Pricing 17%, MRA or 24% or MRA 17%, MRA Generics U&C Dispensing lee $1.65IRx $O/Rx $1,65/Rx Administrative fee $DIRx $O/Rx $DIRx Rebates - Rebate Guarantee $2.00IRx $9,OOIRx $9,OOIRx Per Claim . If the calculation of fhe cost of the claim is less than Express Scripts' minimum Home Delivery rafe (currently $8,99) end less than fhe applicable copayment, fhen the member will pay the greater oftheAWP discount price, or the Minimum Rate, Express Scripts' Specialty Offering Express Scripts' Exclusive specialty option IS designed to offer clients maximum cosl savings and superior patient care. Under Ihis option, patients obtain all specialty medications through our CuraScript specialty pharmacy at the reimbursement.rates set forth below, Specialty drugs will not be available through other pharmacies except for: . limited distribution products not available at CuraScript . initial courtesy fills as allowed by Sponsor's plan design, and . overrides for urgent situations. City of Carmel Sept 9th, 2008 1 Pricing Supplement STANDARD DISCOUNTS: Except for the specific items iisted in the Exceptions or Limited Distribution tables below, Specialty drugs wiil h h f ' ave t e oilowlnQ discounts: Distribution Channel Standard Discounts DispensinQ Fee CuraScript . The lower of: . AWP -15%, or $0.00 . MRA Participating Pharmacies The loweat of: . AWP - 15% plus Dispensing Fee $2,00 . MRA plus Dispensing Fee or . U&C Specialty products will not be available through the Express Scripts Mail Service Pharmacy, Limited Distribution Drugs Distribution of a small number of ail specialty drugs is limited by the manufacturer to specific pharmacy providers, The drugs, listed below, are not available through CuraScript. If CuraScript receives a prescription for one of the following Limited Distribulion medications, CuraScript will: . . Determine the pharmacy that is able to dispense the medication, . Validate that the pharmacy is contracted to provide the medication based an the patient's insurance information and will: o Work with. the patient and prescribing physician to initiate the transfer of the script to the appropriate pharmacy for tUlfillment, or o Provide the patient and physician with information regarding possible patient assistance programs. The cost of the medication wiil be billed through your regular invoice if il is a covered product. ADAGEN FLOLAN REMODULlN APOKYN KEPIVANCE SOMAVERT ARALAST MIRENA VENTAVIS ARCALYST ORFADIN XYREM BEXXAR I ORTHOCLONE OKT-3 ZEMAIRA CEPROTIN I PRIVIGEN ZEVALlN EXJADE PROLASTIN Drug,Name Exceptions to Standard Pricing The following speciaily drugs have the discounts shown for each distribution channel. Shaded ceils indicate the Standard pricing above appliea for Ihe channel indicated, City of Carmel Sept. 9th, 2008 2 Pricing Supplement Retail, CuraScript. % Discountfrom AWP .'to DiscounifromAWP ADVATE I 25.0% ALPHANATE 25.0% ALPHANINE 25.0% ATGAM BEBULlN BENEFIX BONIVA 13,0% 13,0% BOTOX CELLCEPT CIMZIA CYCLOSPORINE EUFLEXXA FEIBA 25,0% FORTEO 13.0% 13.0% HELlXATE FS 25,0% HEMOFIL M 25,0% HUMATE-P 25,0% HYALGAN IMPLANON 00 0,0% IRESSA 13,0% 13,0% KOATE-DVI 25,0% KOGENATE 25,0% LUPRON LUPRON DEPOT METHOTREXATE MONARC-M 25.0% MONOCLATE-P 25.0% MONONINE 250% MYOBLOC NOVOSEVEN 25,0% ORTHOVISC PROFILNINE 25,0% PROGRAF RECLAST 13.0% 13,0% RECOMBINATE 25,0% REFACTO RIBAPAK 25.0% RIBASPHERE 25,0% RIBATAB 25,0% RIBAVIRIN 50,0% SANDIMMUNE SOMAVERT 10,0% SUPARTZ SYNVISC I XYREM 12,0% I ZENAPAX I UPDATES Express Scripts updales the specially drug lists as new products are introduced to the market, or as CuraScript gains access to additional limited dislribulion drugs, and provides a monthly notice of added drugs. Pricing for these new products will be determined by Express Scripls and Sponsor will have the option of covering or not covering the medication. The full current list is always available on request from your Account team. City of Carmel Sept. 9th, 2008 3 pricing Supple'ment Assumptions Quoted fees and services are'validfClI' 90 diys from the date of the, proposal. Quoted, fees are guaranteed for the term of the 3-yearcontract. Minimum of] ,400lives will. be inlplemeh!ed on the effective date, None ofthe menibershilllo be enrolled. is based on'a 100% copaymentbenefit plao, Express Scripts reserves the right t!?"amend the price'quotation set' forth herein ifthere is a material changeih,the oumber.ofpersons,included'in theprescrip;ion drug progr!lm or any material change in'the oenefitpfan from that which waspresentedto Express' Scripts and uponwhicli this price quotation is based, . City of CarrheLagreesto adopt Express/Scripts, National Preferred Formulary, in ordedobe eligible for rebale,s, wh~ther rebates;are paid or'applied. . Rebateguarantees,assumethe current benefit pl?n design, or newbehefii plan design as disc1ose.d bytne .client, \vill be implementedatthe time these,guarantees go into effect. Rebate guarantees are subj,e,fto adjustment ifanyClinical 6i' trehdprograms'ilitcnded to drive higher generic or over-the-counter (OTC) utilization arecurre;nly inplace'~vithout Express Scripts' kngwledgeOf both the program, and drugs'within the'.program, Rebate guarantees are also subjecl)O adjustment if the clien(chooses t6 impJemeotahy clinical or trend tnaoilgemeht'programsintended to drive,higher generic or OTC utilization duringlhe course,oftl1e'contract, Rel5ates.are paid onlyupon receipf:ofa signed.contract Rebates are paid on special,t)' products dispensed through CuraSi:ripl or participating fetail pharmacies, . Rebate, allocations will bemade,quari.erly within 150 days from the end of the quarter . The ,rebate guarantee does 110t apply to claims processed;throughstaff'modellhos[lital pharmacies where,such pharmacyis'subjectto its own manufacturer contracts (rebate,or purchase discounts), or.through pharmacies that participate,in ~he Federal govefnnient pharmaceutical.puich.asi'ig program, ' The parties uoderstand.ihat pricin,gindices historicalty used, (and that are the l5asisin'this Agreement), for'determihilig.the financial, cOOlponentsofpharmacy billing rates'are outside the controf of City of<;:armel,and Express Scripts. The,parties,also understand,tljat there ,are currently extra-market industry, legal, government, andr~guliitoryactivities, which may lead to chal)ges, relatilig to,.br elimination of; lhesepricing indices that.cpuld alter the fir.ancia! positions orthe panies as infended'under ,tlll,s Agr,eemenl. The parties agree that, upon enteringinto,ahy.resultal1l Agreement aod.thereafter, theirmut,ual int,~ntha:sbeen and is to maintain pricing stability as'iiitended.and ilotto'advantage either partytQ.,thedetrimenl'ofthe other, Accord'ingly. to preserve this mutual intent; if Express Scripts 'undertakes aoyor all of the,following: (i) changesthe:A WP sourceacross,{ts bookof bus mess (<:,g" from First DataB,ank to MediSpan); or' City of Carmel Sept. 9th, 2008 4 Pricing Supplement (ii) maintains A WP as the pricing index with an appropriate adjustment as descrihed below; in the event the A WP methodology and/or its calcu lation is changed, whether by the existing Or alternative sources; or Ciii)transitions tbe pricing index from AWP to another index or bencnmark (e,g., to Wnolesale Acquisition Cost), the Participating Pharmacy, Curascript, and Mail Service Pharmacy rates, rebates and guarantees, as applicable, will be modified as reasonably and equitably necessary to maintain the pricing intent under this Agreement. Express Scripts sball provide City of Carmel with at least ninety (90) days notice of the change (or ifsuch notice is not practicable, as much notice as is reasonable under thc circumstances), and written illustration of the financial impact of the pricing source or index change (e,g., specific drug examples). If City of Carmel disputes the illustration or the financial impact of the pricing source, the parties agree to cooperate in good faith to resolve such disputes. . For each eligible prescription-drug claim, ingredient cost will be calculated at the lesser of the applicable U&C, MRA, or A WP discount price in determining the discount achieved for purposes of the guarantee, including 100% member copayment (claims where full cost is paid by member). City of Carmel Sept. 9th, 2008 [; Included Services Pricing Supplement Express Scripts' administrative fee, jncludes theJollowirig'syrvices: PBrIlSeryices Customer service for members Electronic/an"lirie eligibility submission " Standard.coordination of'benefits,(COB) (reject for pri~a,ry ~arrier) FSA eligibility feeds Network' PharrT1~cy S~'Y!ces Pharmacy help desk ,. p~armacynetworkmanagement , HOrne DeliveryiSe.vlces Benefit education " Reportiri~iS"rVices Web-based client rePorting - produced by client Ad-hoc desktop parametric 'eports Claims detai;"extracl frle,electro;nic:(NCPQP format) Load:12 !!lonths claims history tor clinical ,eports " . an?, reporting ~ Websi'te;Sel"\llces Express-Scripts,com.tor qiie"ts & Advisors ~ ~ccess'!o reportii1g lools, eligibilitYupdafe capability, caritact directory: sales and marketirig,information, and benefit and'enrallment support ExpresscScripia,comfor lVi;,mbers - access to ben'efit, drug, health and wellness information; prescriptTon' ordering,capability; and customer, service . : linp'g;"i)),~r)i~liqn RackageandMemberCommunicatlOns, New member'packets {includes two standard resin H)'cards) . . Member replacementcards printed,via web 'Safel)l:Managemenl 'Concurrent Dru~Util;zation Review (DUR) T. reni:t:Niarlage'meht, .' .'---'~ ".. ". -. - .'.. Prior Authorization--Administrative Non-clinical Pdor A~thqriza1ion LosUsto~eri overrides VacaUonsuppliea City of Carmel Sept...9th,2008 E!ettran.ic:daims "processing Planaetup Software, training for access-to our .on-line '," -.. P' .-.. .,"... . '-. ..- 'sX5Iem(s) Ptlahllacy-reimbursement _. Network development (upon request). Prescription'deliveiy - standard Annual Strategic'Account Plan report 'Biilirig'reports ... " J nqui ryeccess.to claims" processing ,system. Express Preview'M enrollment option - available 'during open enrollment 10 enable,members to ~evaluale pr€scripllon benefit pIan options Digital Certificates.(up.to fivecertificales) I mp)ementatlon:su PP<1rt EmeigingTlierapeutics Prior Authorization - Cliiiical Base List Blood Glucose Metef' pr6g'ra'm ' Tlierapeulic Interchange. 6 Additional PBM Services Pricing Supplement PBM services 'r'o .",-- Manual/hardcopy eligibility submission Member Submit (ee (includes Medicaid.subrogation claims Fees' $1,OOlupdate (includes initial enlry) $2.50Iclalm ",+. .. - Netw6r~'Pha rmacy 'Senii ces, .~ ----= "- " ".' Pharrnac audit recoveries Repoi1ingServices. ^. '-,' .~.. Web-based client reporting produced by Express Scripts Custom ad'hoc reporting RepiacemelitMember,C6niriiiJrilcatiOn PacketS. . ~ ,'" .'-' ". 'L'_ . ,",',' .,... _J ' Member requested replacement packets Clientre uested re-cardin i_.ApP'~als11iY:MCMC . ---" . .."" -.~ . Clinical appeals . Non-clinical appeals 20% of audit recoveries $100lrepon $150/hour, with a minimum of $500 $350/review S160/review . Plana subject to state law (non-ERISA plans) will be charged a retainer lee 01$1,000 per monte for appeala handled b MCMC MedIcllrll,Pa'hO; d~ ,-<'> . Part 0 Subsidy enhanced service (Express Scripts sends repons to cMs on behalf 01 client) . Notice of Creditable Coverage . Part o Subsidy standard service (Express Scripts sends repons to client) . Notice of Creditable Coverage . Using Outside Cost ReporterNendor (ESI provides final rebate fi ures rtIe<!ic''fre:PiI(!tl . Pan B Services (Retail and Mall Benefit) $1.12 PM PM for Medicare-qualified members with a minimum annual fee 01$7,500 $1,35/letler + postage $062 PMPM for Medicare-qualified members wilh a minjmum ann'ualfee of $5,000 $1,35/leller + postage $0.42 PM PM $0.42 PM PM for Medicare-qualified members City of Carmel Sept, 9th, 2008 7 Pricing Supplement Optional Total Health al'!d'Trend l\IIanagem~nt Services Express Scripts offers'a.'corhprehensive,slliteoftrend 'and total healtlFmanagement'programs. We 'q - . have identified'programsb~low.mostoften imp]emented.byour,p]an s'pohsors, .This olferi~g jnay change onbe i:1iscontinlled from time to time as we' U p,d ate 'our offering to meet the,needs ofthe, ,mark~tp]ace. Expres,sScriptsalso.offe'rs additional prograins,aswe]l as savings:guarantees, under ce,l1ain'cond[tiqns, Information concef!liilg'~ucbprograri1s, guarmltees, andfe.es, if applicahle, is'available on request. Trend Manag.~mentil?rograms Drug Quantity Management" Prior'Authorization - Cllnicai Supplemental List" Prior Authorization -Oiher Clinical Overrides (e.g. non. standaro .Prior AuthorizaXioD 'Dedications, medical excepllons) Step Therapy- individual modules'and packages available More than 25 modules available. the mO'SI I1tilized'inClude: ACElnhib1!ors.a'nd angibtensln"2,eceptorblackers (ARBs), non-steroidal a'nii.innammatory drugs (NSAIOS) and COX.2s, proton'pump-inhibiiors (PPls), selectiveaerotonin reuptake. ,lIlliibitors (SSRis): Hrv\G'enha,k~d 2al~ium' chan6el bloclierS, 'Ieuk.otri,me pathwayinhibitars:topical immunomoaulators, olherantidepressanls: Formulary Rapid Response SO GenericCop~y . List of drugs subject tochangeaithedi~cretion oftxpress Scripts, F~~s $002;PMPM $O,o'3PMi"M "$20/request' $25/physicianreview Pri.ci~g varies. by module $0:01 PMPM S1.25/member mailing or $1,OoOfor mem beLldentJfl Qatiqn. and, aut&orh:ation T6talHea Ith'Ma1i"gemenlJ>tQ'gfams~. .> - -~ . . ".-- .- . .", ',-. :.'.., .- , Ma.!l~ging,Me<!iSe,tl,OI'! :r;her~pY:~,f,](S,,~ely Medicallon Adherence Retrospecliva.DUR RelrOSoeclive OUR - Seniors RxPredict$ Fe,eSJ $o,02,PMPM lIicludes,allseven modules $O,03/Rx W02/R~ $0,05 PMPMfor.six months each,time t,he report is run (e.g: 100,000 members. '$005 PMPM . six months). A sJbsequenlcharge willoccu'rwith the second.J~p.ort. The~eds a'minimum charee of $3,000. '.' ,-~ . Maraging,Overal! liealtll Car" Management Disease Management Tllre~-~i-sease: suite' Fi\ie".disease suite S'ix-dlsease .suite City of Carmel Sept. 9th, 2008 $OOt/claim Asthma $O.01iclaim ~ Cardiovascular Disease $O,02/C1aini - CHF $0,02/claim -Depression $O:Ot/claim'- Diabetes $O:.03/claim - 81 Disease $0.02/c1aim- Hypertension $O,02iclaim ~ Mi raine Priced upon.request 8 Pricing Supplement Total Health Managemeni;Programs" . Fees .."._ ..... '0'__ ,-.. __ ._, p __ ExpressAlliance Levei 1 5,000-20,000 ,lives $0,04 PMPM 20,000-50,000 lives $0.02 PMPM 50,000+ lives $001 PMPM ExpresaAlllance Level 2 5,000-20,000 lives $0,20 PMPM 20,000-50,000 lives $O,1OPMPM 50,000+ lives $0.09 PMPM ExpressAlliance Lever3 5,000-20,000 lives $0.35 PMPM 20,000-50,000 lives $0.20PMPM 50,000+ lives $0.18 PMPM RxPredict$ $0.05 PMPM for six months each time the report is run (e,g, 100,000 members' $0.05 PMPM' six months), A subsequenl charge will occur with the second report. There is a minimum charne of $3000. High Utilizer & Case Management Report $150/report ,. All programs are optional and will only be Implemented upon client request City of Carmel Sept. 9tt!, 2008 9 Pricing Supplement Billing and Payment Billing Information' Billing Frequency Payment Options. Weekly or twice per month Wire Transfer Payments must be transferred within two days of receipt of the Express Scripts invoice/billing statement Payments must be made within two days of receipt of the Express Scripts invoice/billing statement Automated Clearing House (ACH) Pre-Aulhorized Debit Funds must be available in the client's bank account within 48 houraof receipt Tranaaction of the Express Scripts invaicelbiiling statemenl Please note that each client is subject to a standard credit evaluation, City of Carmel Sept. 9th, 2008 10 Pricing Supplement Financial Disclosure to Express Scripts Clients Express Scripts is a provider of pharmaceutical benefits management ("PBM") and other related services to thousands of client groups including managed care organizations, health insurers, employer groups, third-party administrators and government entities, Express Scripts' subsidiary companies, some of which provide services related to supporting our PBM services, include Express Scripts Mail Pharmacy Service, lnc" CuraScript Pharmacy, Inc" Express Scripts Specialty Distribution Services, Inc" and Phoenix Marketing Group, LLC. This disclosure provides an overview of the revenue sources that allow us to deliver competitive pricing arrangements to our clients, Express Scripts offers its clients, either directly or through its subsidiary companies, a variety of services related to the management of prescription drug benefits, The specific services provided to each client are documented under the Pharmacy Benefit Management Agreement, or other similar agreement, with our client Express Scripts' PBM services typically include claims processing and adjudication, pharmacy network contracting and management, formulary development and managemenl, rebate management and administration, trend management, and clinical program development and fulfillment, Some of our clients also utilize our mail service pharmacy to provide their members with convenient access to safe and affordable prescription drugs through home delivery, In addition to the administrative fees paid to us by our clients for these core PBM services, Express Scripts derives revenue from other sources, including arrangements with pharmaceutical manufacturers and retail pharmacies. Some of Ihis revenue relates to utilization of products by members of the clients for whom we provide PBM services. Network Pharmacies - Express Scripts contracts for its own account with retail pharmacies to dispense prescription drugs to members of the clients for whom we provide PBM services, The rates paid by Express Scripts to these pharmacies differ from one network of pharmacies to the next, and among pharmacies within a network, Express Scripts generally contracts with clients 10 be paid an ingredient cost for drugs dispensed in a given retail network selected by the client at a uniform rate that applies to all pharmacies in the selected network, Thus, where the rate paid by a client exceeds the rate negotiated with a particular pharmacy, Express Scripts will realize a positive margin on the applicable prescription, The reverse may also be true, resulting in negative margin for Express Scripts, In addition, when Express Scripts receives payment from a client before payment to a pharmacy is due, Express Scripts retains the benefit of the use of the funds between these payments, Manufacturer Rebates and Associated Administralive Fees - Express Scripts contracts for its own account with pharmaceutical manufacturers to obtain rebates attributable to the ulilization of certain prescription products by individuals who receive benefits from clients for whom we provide PBM services, Rebate amounts vary based on the volume of utilization as well as the benefit design and formulary position applicable to utilization of a product. Express Scripts often pays all or a portion of the rebates it receives to a client based on the client's PBM services agreement, Express Scripts retains the financial benefit of Ihe use of any funds held until payment is made to a client. In connection with our maintenance and operation of Ihe systems and other infrastructure necessary for managing and adminislering the rebate process, Express Scripts also receives administrative fees from pharmaceutical manufacturers participating in the rebate program discussed above, The services provided to participating manufacturers include making certain drug utilizalion data available, as allowed by law, for purposes of verifying and evaluating the rebate payments, Administrative fees retained by Express Scripts in conneclion with its rebate programs do not exceed 3,5% of the A WP of the produclS for which rebates are payable 10 Express Scripts, Pharmacy Dispensing and Distribution - Express Scripts has several licensed pharmacy subsidiaries, including our specialty pharmacies. These entities purchase prescription drug inventories, either directly from manufacturers or from drug wholesalers, for dispensing to patients or for distribution to physician offices, Purchase discounts off the acquisition cost of these products are made available by City of Carmel Sept. 9th, 2008 11 Pricing Supplement manufacturers in the form of both up-front and relrospective discounts, Such discounts are not considered part of the rebates paid to Express Scripts by manufacturers in connection with our rebate program, While rebates are directly attributable to the utilization of pharmaceutical products by individuals who receive benefits from clients for whom we provide PBM services, product acquisition price discounts are based on a pharmacy's inventory needs and, in the case of specialty pharmacies, the perfomlance of related patienl care service obligations, The purchase discounts obtained by these facilities are not based on any client's benefit design, When an Express Scripts subsidiary pharmacy dispenses or distributes a product from its inventory, the purchase price paid for the dispensed product, including applicable dispensing fees, may be greater or less than the pharmacy's acquisition cost for the product net of purchase discounts, In general, our pharmacies realize an overall positive margin between this net acquisition cost and the amounts paid for the dispensed products, Pharmaceutical Program Services - Our specialty pharmacies, including CuraScript Pharmacy, Inc, and Express Scripts Specialty Distribution Services, Inc" receive compensation from manufacturers for their administration of programs related to the distribution of certain pharmaceutical products, This compensalion is based on the fair market value of the services provided and is unrelated to the drug formulary development process or drug utilization applicable totheclients for whom we provide PBM services, Examples of Ihese services include (i) administering patient assistance programs for indigent patients; (ii) administering product sample distribution programs; and (iii) dispensing prescription medications 10 patients enrolled in clinical trials, Data Reporting - Express Scripts sells certain data resulting from its PBM and pharmacy services to healthcare data aggregators and similar entities from time .to time, We do not sell any data unless we are permitted to do so by the terms of our client contract and by applicable patient privacy laws, In addition, as a condition to receiving access to certain products, a specialty phannaceutical manufacturer often will require a purchasing specialty pharmacy to report selected information to the manufacturer regarding the pharmacy's service levels and other de-identified dispensing-related data with respecl to patients who receive such manufacturer's product A portion of the discounts or other compensation made available to our specialty pharmacies represents compensation for such reporting, All such reporting activities are conducted in compliance with applicable patient privacy laws, Other Pharmaceutical Manufacturer Services - Phoenix Marketing Group, LLC special izes in the provision of sample fulfillment, sample accountability, alternative sampling, direct mail fulfillment, and literature fulfillment services for pharmaceutical manufacturers, Because ilsservices involve only warehousing and fulfillment-related functions, this subsidiary entity does not review products clinically and it never uses" sells or has access to Express Scripts' client or member information, Compensalion paid to Phoenix Marketing Group, LLC by pharmaceutical manufacturers is based on the fair market value of such services, as established most often through an "RFP" process, and any such compensation is unrelate~d to the drug formulary development process or drug utilization applicable to the cliems for whom Express Scripts,provides PBM services, Revised July, 2005 Express Scripts does nol conduct business in a fiduciary capacity to plan sponsors or members, Express Scripts exercises no discretion with respecno the management of the plan or control of plan assets. City of Carmel Sept. 9th, 2008 12